Skip to main content

Ensemble Learning Approach for Stability Prediction of Interface and Core mutations (ELASPIC).

Project description

# ELASPIC

[![anaconda](https://anaconda.org/kimlab/elaspic/badges/version.svg?style=flat-square)](https://anaconda.org/kimlab/elaspic) [![docs](https://img.shields.io/badge/docs-latest-blue.svg?style=flat-square&?version=latest)](http://kimlaborg.github.io/elaspic) [![travis](https://img.shields.io/travis/kimlaborg/elaspic.svg?style=flat-square)](https://travis-ci.org/kimlaborg/elaspic) [![codecov](https://img.shields.io/codecov/c/github/kimlaborb/elaspic.svg?style=flat-square)](https://codecov.io/gh/kimlaborg/elaspic)

## Introduction

Welcome to the ELASPIC code repository!

Complete documentation is availible on [ReadTheDocs](http://elaspic.readthedocs.io).

For a small number of mutations, you can try running ELASPIC using our [webserver](http://elaspic.kimlab.org).

## References

Witvliet D, Strokach A, Giraldo-Forero AF, Teyra J, Colak R, and Kim PM (2016) ELASPIC web-server: proteome-wide structure based prediction of mutation effects on protein stability and binding affinity. Bioinformatics (2016) 32 (10): 1589-1591. doi: [10.1093/bioinformatics/btw031](https://doi.org/10.1093/bioinformatics/btw031).

Berliner N, Teyra J, Çolak R, Garcia Lopez S, Kim PM (2014) Combining Structural Modeling with Ensemble Machine Learning to Accurately Predict Protein Fold Stability and Binding Affinity Effects upon Mutation. PLoS ONE 9(9): e107353. doi: [10.1371/journal.pone.0107353](https://doi.org/10.1371/journal.pone.0107353).

Project details


Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distribution

elaspic-0.1.33.tar.gz (9.5 MB view hashes)

Uploaded Source

Supported by

AWS AWS Cloud computing and Security Sponsor Datadog Datadog Monitoring Fastly Fastly CDN Google Google Download Analytics Microsoft Microsoft PSF Sponsor Pingdom Pingdom Monitoring Sentry Sentry Error logging StatusPage StatusPage Status page