DICEseq: Dynamic Isoform spliCing Estimator via sequencing data
Project description
# DICEseq: Dynamic RNA splicing estimator via sequencing data
## About DICEseq DICEseq is a Dynamic RNA splicing estimator via sequencing data. It could quantify alternative splicing isoform or RNA splicing ratio, i.e., proportion of mature mRNA from pre-mRNA. More generally, the program is designed object-oriented for transcripts. Thus, it supports arbitrary transcript, with customised the coordinates of exons and introns. It also supports addition and removal of specific transcripts.
This program also provides customised reads counting, especially boundary/junction reads, normalisation, reads simulation, sequencing bias correction, etc.
Currently, the program for static quantification has been tested on the simulated and real data and showed good performance, but the dynamical model is still in preparation.
## More information See the homepage of DICEseq [here](http://diceseq.sourceforge.net), and documentation on how to install, how to use etc [here](http://diceseq.readthedocs.org).
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