Exonviz

Visualise exons

Usage

Pass either a transcript (with version!), or a valid HGVS description to exonviz to generate a figure.

Options

Since each gene is different, you will probably want to play around with the options to get the perfect figure for your favorite gene.

usage: exonviz [-h] [--max-width MAX_WIDTH] [--height HEIGHT] [--non-coding]
               [--gap GAP]
               transcript

Description of command.

positional arguments:
  transcript            Transcript (with version) to visualise

optional arguments:
  -h, --help            show this help message and exit
  --max-width MAX_WIDTH
                        Maximum width of the figure (default: inf)
  --height HEIGHT       Exon height (default: None)
  --non-coding          Show non coding regions (default: False)
  --gap GAP             Gap between the exons (default: None)

Examples

SDHD

Using the default settings, which does not include non-coding regions of the exon:

exonviz "NG_012337.3(NM_003002.4):c.274G>T" > SDHD.svg

DMD

Since DMD has many exons, we specify a maximum width for the figure:

exonviz "NM_004006.3:c.=" --max-width 1024 > DMD.svg

ATXN1

Include the non coding exons, since most exons of ATXN1 are non coding. We limit the maximum width and increase the height of the picture. For clarity, we also increase the distance between the displayed exons:

exonviz ENST00000436367.6 --non-coding --max-width 4000 --height 150 --gap 50 > ATXN1.svg

PLP1

Include the non coding regions and increase the height and distance between the exons:

exonviz "NM_000533.5" --non-coding --height 100 --gap 50 > PLP1.svg

NF1

Set the maximum width of the figure to the approximate size of the largest exon:

exonviz "ENST00000358273.9" --non-coding --max-width 3600 --height 75 --gap 20 > examples/NF1-202.svg